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Experimental Biology and Medicine 228:434-440 (2003)
© 2003 Society for Experimental Biology and Medicine


ORIGINAL RESEARCH ARTICLE

Effects of Resistance versus Aerobic Training on Coronary Artery Disease Risk Factors

William J. Banz*,{dagger},1, Margaret A. Maher{ddagger}, Warren G. Thompson**, David R. Bassett||, Wayne Moore, Muhammad Ashraf§, Daniel J. Keefer|| and Michael B. Zemel§

* Departments of Animal Science, Food and Nutrition and
{dagger} Physiology, Southern Illinois University, Carbondale, Illinoios 62901;
{ddagger} Department of Biology, University of Wisconsin, La Crosse, Wisconsin 54601; and
§ Departments of Medicine,
|| Human Performance and Sport Studies, and
Nutrition, University of Tennessee, Knoxville, Tennessee 37996; and the
** Mayo Clinic, Rochester, Minnesota

Individuals exhibiting "the metabolic syndrome" have multiple coronary artery disease risk factors, including insulin resistance, hyperlipidemia, hypertension, and android obesity. We performed a randomized trial to compare the effects of aerobic and resistance training regimens on coronary risk factors. Twenty-six volunteers who exhibited android obesity and at least one other risk factor for coronary artery disease were randomized to aerobic or resistance training groups. Body mass index, waist-to-hip ratio, glucose, insulin, body composition, 24-hr urinary albumin, fibrinogen, blood pressure, and lipid profile were measured at baseline and after 10 weeks of exercise training. Both groups showed a significant reduction in waist-to-hip ratio and the resistance training group also showed a reduction in total body fat. There was no significant change in mean arterial blood pressure in either group. Fasting plasma glucose, insulin, total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides were unchanged in both groups. High-density lipoprotein (HDL) cholesterol increased (13%) with aerobic training only. Plasma fibrinogen was increased (28% and 34%, P < 0.02) in both groups and both groups showed a significant decrease (34% and 28%, P < 0.03) in microalbuminuria after their respective training regimen. In conclusion, resistance training was effective in improving body composition of middle-aged obese sedentary males. Only aerobic training was effective in raising HDL cholesterol. More studies are warranted to assess the effects of exercise on plasma fibrinogen and microalbuminuria.

Key Words: insulin resistance • metabolic syndrome • resistance training • aerobic training • coronary artery disease




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